Non-steroid anti-inflammatory drugs, prostaglandins, and cancer

Nonsteroidal anti-inflammatory drugs: prostaglandins, indications, and side effects

Correspondence: Peter v Giannoudis Academic Department of Trauma and Orthopaedics, Leeds Teaching Hospitals NHS Trust, Clarendon wing, Great George St, Leeds LS1 3eX, UK Tel +44113 3922750 email [email protected] Abstract: For centuries, nonsteroidal anti-inflammatory drugs (NSAIDs) have been part of our clinical practice. They started out as drugs with anti-inflammatory and analgesic action, ...

Non-Steroidal Anti-Inflammatory Drugs, DNA Repair and Cancer

Non-steroidal anti-inflammatory drugs in cancer prevention and therapy.

Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) can be regarded as an effective approach for cancer chemoprevention, as demonstrated by a bulk of clinical and experimental evidence. However, the clinical use of these drugs as chemopreventive agents is limited by many open questions about the optimal drug, dose, duration of therapy and knowledge about the mechanism(s) by which th...

Non-steroidal anti-inflammatory drugs and colorectal cancer prevention.

Colorectal cancer is the second leading cause of cancer deaths in the United States. Currently, the most effective strategy available for colon cancer prevention is endoscopic screening, with polypectomy or surgical resection for advanced lesions. This intervention carries with it many concerns regarding cost, patient acceptance, and the growing burden of surveillance colonoscopies for patients...

Non-steroidal anti-inflammatory drugs.